Wnt5A signaling pathway helps researchers determine who may respond to BRAF...
One of the challenges of understanding cancer is trying to determine the mechanisms that drive metastasis, or the process by which tumor cells are able to spread throughout the body.
View ArticleNew small-molecule inhibitor shows promising results in drug-resistant...
LEE011, a small-molecule inhibitor of cyclin-dependent kinases (CDK) 4/6 being developed by Novartis Oncology, showed promising results in drug-resistant melanoma and drug-resistant breast cancer when...
View ArticleNew MDx prototype platform can detect BRAF V600 mutations in 90 minutes
A new diagnostic platform to detect BRAF mutations in melanoma and other cancer types is faster and more accurate compared with the standard method currently used in clinics, and this could help...
View ArticleFunctional biomarker could help guide treatment of patients with BRAF-mutant...
A functional biomarker that can predict whether BRAF-mutant melanomas respond to drugs targeting BRAF could help guide the treatment of patients with these cancers, according to results presented here...
View ArticleVivaScope imaging allows physicians to "see" below surface of skin to...
A relatively well-known tool to diagnose melanoma has recently come under criticism for two reasons: its inability to detect non-melanomas, and its dependence on the use of computerized...
View ArticleAMP 2013: EKF Molecular Diagnostics to launch four new PointMan DNA...
EKF Diagnostics, the global diagnostics business, announces that EKF Molecular Diagnostics will launch four new PointMan DNA enrichment kits at the Association for Molecular Pathology Annual Meeting...
View ArticleResearch: New drugs show ability to rapidly shrink melanoma tumors
Melanoma is the deadliest form of skin cancer, killing more than 8,000 in the U.S. each year. Approximately 40 percent of advanced melanoma tumors are driven to grow by the presence of mutations in a...
View ArticleCombinatory therapy may be effective in suppressing drug resistance in...
Stand Up To Cancer (SU2C), the charitable initiative supporting ground-breaking research aimed at getting new cancer treatments to patients in an accelerated timeframe, announces that the Allan H....
View ArticleStudy highlights need for ongoing surveillance for melanoma survivors
Melanoma survivors are being warned to stay vigilant about skin checks, with new research showing a high risk of a subsequent melanoma diagnosis on the same body part as the original.
View ArticleScientists receive $12.5M NIH grant to continue research on targeted...
Despite recent advances in therapy, melanoma remains the deadliest, most aggressive form of skin cancer as incidence rates continue to climb. Now, a team of melanoma scientists from The Wistar...
View ArticleOncoSec Medical reports positive interim data from OMS-I100 Phase 2 trial for...
OncoSec Medical Inc., a company developing its advanced-stage ImmunoPulse DNA-based immunotherapy to treat solid tumors, today announced positive interim data from its ongoing Phase 2 trial of OMS-I100...
View ArticleResearchers identify two novel BRAF fusions in melanomas
Stand Up To Cancer, the charitable initiative supporting ground-breaking research aimed at getting new cancer treatments to patients in an accelerated timeframe, announces that Jeffrey A. Sosman, M.D.,...
View ArticleBRAF mutation associated with other cancers appears to drive papillary...
A team led by investigators from Massachusetts General Hospital, Brigham and Women's Hospital and the Broad Institute has found that a gene mutation associated with several types of cancer also may be...
View ArticleScientists develop novel treatment for Hairy Cell Leukaemia using drug...
A team of scientists from the University of Leicester has demonstrated a novel treatment for Hairy Cell Leukaemia (HCL), a rare type of blood cancer, using a drug administered to combat skin cancer.
View ArticleAdvanced melanoma treatments: an interview with Dr. James Larkin, Consultant...
Advanced melanoma affects around 2,000 people per year in the UK. Advanced melanoma describes a melanoma that has spread from its site of origin to other areas of the body.
View ArticleIncidence of skin cancer increased nearly eightfold among middle-aged men and...
A new Mayo Clinic study found that among middle-aged men and women, 40 to 60 years old, the overall incidence of skin cancer increased nearly eightfold between 1970 and 2009, according to a study...
View ArticleStudy provides extensive review of incidence, risk factors and...
While people of color have a lower risk of developing skin cancer than Caucasians, they are not immune to the disease. In fact, skin cancer is often diagnosed at a more advanced stage in people of...
View ArticleStudy affirms new standard for detecting melanoma metastasis to the lymph nodes
Long-term research that was initiated at UCLA's Jonsson Comprehensive Cancer Center on lymphatic mapping and sentinel-node biopsy, techniques for detecting the earliest spread (metastasis) of melanoma,...
View ArticleCertain fragments of DNA shed by tumors can be used to non-invasively screen...
Certain fragments of DNA shed by tumors into the bloodstream can potentially be used to non-invasively screen for early-stage cancers, monitor responses to treatment and help explain why some cancers...
View ArticleSunburn causes melanoma through direct and indirect processes
Melanoma is particularly dangerous because it can form metastases in vital organs such as the lungs, liver or brain. UV radiation is considered to be the most significant triggering factor.
View Article
